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Projects:

• Probing the active sites of adenosylcobalamin dependent glutamate mutase and 2-methyleneglutarate mutase.
• Exploring the biological degradations of organohalides in the environment for prospective biotechnological applications against organohalides contaminations.
• Structure based approaches toward developments of anti-tubercular and anti-fungal agents.

Publications:

1. Lyatuu, F. E and Buckel, W. (2021) Kinetic Studies of a Coenzyme B₁₂ Dependent Reaction Catalyzed by Glutamate Mutase from Clostridium cochlearium. Advances in Enzyme Research, 9, 72-90. doi: 10.4236/aer.2021.94007.
2. Lyatuu, F.E., Parthasarathy, A., Zhoi, K., Zelenka, K., Zelder, F.H., Buckel, W. (2012). Probing the Cob(II)alamin Conductor Hypothesis with Glutamate Mutase from Clostridium cochlearium. Proceedings of the 2^nd Tanzania Chemical Society International Conference. 5^th -7^th October, 2011. Dar es Salaam, Tanzania, Tanz. J. Sci., 38(3), 148- 156
3. Friedrich, P., Baisch, U., Harrington, R. W., Lyatuu, F., Zhou, K., Zelder, F., McFarlane, W., Buckel, W. and Golding, B. T. (2012), Experimental Study of Hydrogen Bonding Potentially Stabilizing the 5′-Deoxyadenosyl Radical from Coenzyme B₁₂, Chem. Eur. J., 18: 16114-16122 doi: 10.1002/chem.201201840
4. Zhou, K., Oetterli, R. M., Brandl, H., Lyatuu, F. E., Buckel, W. and Zelder, F. (2012), Chemistry and Bioactivity of an Artificial Adenosylpeptide B₁₂ Cofactor, ChemBioChem, 13: 2052–2055 doi: 10.1002/cbic.201200429
5. Kaoneka B, Mollel M, Lyatuu F, (2007), Leaf essential oil composition and tick repellency activity of Commiphora swynnertonii Burtt, J. Biol. Res.-Thessalon, 8: 213 – 21